Mfg Part Number
Ab01549-1.1
Vector Labs Ab01549-1.1 Anti-CD106 [B-K9 (C106-K9)], Mouse IgG1, kappa (200 μg)
Quick Overview
This antibody was raised by immunizing Balb/c mice against activated human umbilical vein endothelial cells (HUVEC).
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | B-K9 (C106-K9) |
| Synonyms: | VCAM1; Vascular cell adhesion protein 1; V-CAM 1; INCAM-100 |
| Amount: | 200 μg |
| Application Codes Clone: | blocking; FC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | B-K9 antibody recognizes CD106 (VCAM1). CD106 is a member of the Ig superfamily. It is a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. |
| Application Notes: | B-K9 antibody inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells, and thus it blocks the ability of white blood cells to attach themselves to the activated epithelium during, for instance, inflammation. Consequently, this antibody might be used in research where leukocytes adhesion-blocking is required (Uotila et al., 2014; Wagner et al. 2011). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |