Mfg Part Number
Ab01581-3.0
Vector Labs Ab01581-3.0 Anti-CCR9 [9B1], Mouse IgG2b, kappa (200 μg)
Quick Overview
This antibody was raised by immunizing rats with KLH-conjugated linear peptide corresponding to the N-terminus of mouse CCR9.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 9B1 |
| Synonyms: | CD199; C-C chemokine receptor type 9; C-C CKR-9; CC-CKR-9; CCR-9; G-protein coupled receptor 28; GPR-9-6; CDw199; 9B-1 |
| Amount: | 200 μg |
| Application Codes Clone: | FC; neutralizing |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | 9B1 antibody recognizes CCR9 at the N-terminus. CCR9 is a member of the G protein coupled receptor family and is involved in T cell development in the thymus and in gut-associated immune response. Mouse CCR9 is highly expressed on different stages of thymocytes and upregulated on CD4+CD8+ cells. |
| Application Notes: | This antibody is recommended for the detection and analysis of CCR9 via flow cytometry (Farazuddin et al., 2019). Furthermore, it was demonstrated that this 9B1 antibody was capable of neutralizing CCR9 function, as it inhibited CCL25-induced calcium mobilization in L1.2-CCR9 cells (Rivera-Nieves et al., 2006). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |