Mfg Part Number
Ab01611-2.0
Vector Labs Ab01611-2.0 Anti-Dynein Light Chain Tctex-Type 3 (DYNLT3) [10A3], Mouse IgG2a, kappa (200 μg)
Quick Overview
The light chain-myosin basic protein fusion protein was expressed in bacteria and the purified fusion protein was injected into mice to generate the monoclonal antibody.
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| Product Class: | Purified |
|---|---|
| Clone ID: | 10A3 |
| Synonyms: | DYNLT3; Protein 91/23; T-complex-associated testis-expressed 1-like |
| Amount: | 200 μg |
| Application Codes Clone: | IP; WB; IF |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody is specific for Dynein Light Chain Tctex-Type 3 (DYNLT1). Dynein Light Chain Tctex-Type 3 acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis (By similarity). |
| Application Notes: | The antibody has been used for immunofluorescence on PC12 cell neurites (Ha et al, 2008; pmid:18559670). Western blot has been performed on PC12 cells using this antibody (Ha et al, 2008; pmid:18559670). It was used for immunoprecipitation on the bacteria expressing the GST fusion proteins (Lo et al, 2007; pmid:17965411). The antibody was used for immunoblot assays on bacteria expressing the GST fusion proteins as well (Lo et al, 2007; pmid:17965411). Mitotic NRK cell lysate has been used for immunoprecipitation with this antibody (Lo et al, 2007; pmid:17289665). Immunoblotting was preformed on Mitotic NRK cell lysate with this antibody (Lo et al, 2007; pmid:17289665). PC12 cell lines were used for a western blot with this antibody (Myers et al, 2007; pmid:17279546). Immunofluorescence was preformed on PC12 cell lines with this antibody (Myers et al, 2007; pmid:17279546). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |