Mfg Part Number
Ab01660-1.1
Vector Labs Ab01660-1.1 Anti-N-cadherin [8C11], Mouse IgG1, kappa (200 μg)
Quick Overview
This antibody was raised by immunizing mice with an extracellular domain of the recombinant human N-cadherin.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 8C11 |
| Synonyms: | CD325; Cadherin-2; CDw325; Neural cadherin; n-cadherin; ncadherin |
| Amount: | 200 μg |
| Application Codes Clone: | WB; IF; IHC; FC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody recognizes human, rabbit and hamster extracellular domain of N-cadherin. It does not cross react with this protein in mouse, rat cow and pig. N-cadherin is a calcium-dependent cell adhesion protein. |
| Application Notes: | 8C11 antibody inhibits cells' motility, as it blocks extracellular domain of N-cadherin which is responsible for this function (Kim et al., 2000). This antibody has also been widely used in the detection and analysis of N-cadherin. For instance, it was utilized to identify this protein in A549 cells via immunofluorescence (Shintani et al., 2011). Another group used successfully 8C11 to analyze the levels of N-cadherin expression via Western blot (Chen et al., 2015). Finally, this antibody was used to label N-cadherin in tumor tissues of a metastasis model via immunohistochemistry (Li et al., 2019). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |