Mfg Part Number
Ab01670-10.3
Vector Labs Ab01670-10.3 Anti-SARS-CoV S glycoprotein [F26G9], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing the BALB/C mice with the Tor-3 strain of the SARS-CoV.
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| Product Class: | Purified |
|---|---|
| Clone ID: | F26G9 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | Spike protein; S protein; SARS-CoV S protein; S glycoprotein; E2; Peplomer protein; Spike protein S1 |
| Amount: | 200 μg |
| Application Codes Clone: | NTRL; ELISA; IF |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody specifically binds the amino acids 318-510 in the S1 domain of the SARS-CoV Spike protein. The originally characterized human IgG1 had a binding affinity of KD=10.2 (±3.5) nM. |
| Application Notes: | This antibody is a SARS-CoV neutralizing antibody. F26G9 was capable of recognising both the S protein and the RBD in an ELISA. The neutralizing mAb, F26G9 specifically recognize SARS-HCoV infected but not uninfected Vero cells in immunofluorescence Immunofluorescence (Berry et al, 2004). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |