Vector Labs Ab01998-23.0 Anti-CD11b [ICRF44], Rabbit IgG, kappa (200 μg) Centrifuge Bundle Savings at Sycamore Life Sciences

Description

Product Class: Purified
Clone ID: ICRF44
Synonyms: Integrin alpha-M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; mAb 44; mAb44
Amount: 200 μg
Application Codes Clone: FC; IHC; WB; IP
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody recognizes CD11b (Integrin alpha-M) which is an adhesion molecule. CD11b associated with integrin beta2 (CD18) is expressed on the surface of monocytes, granulocytes, activated lymphocytes and a subset of NK cells. CD11b is a receptor for intercellular adhesion molecule family members CD54, CD102 and CD50 as well as for iC3b. These adhesions are crucial in cell-cell and cell-matrix interactions.
Application Notes: This antibody is recommended for the detection and analysis of CD11b (Integrin alpha-M) and CD11b-plus cells in lineage identification. The original mouse IgG1 format of this clone has been widely used in various flow cytometry experiments. For instance, ICRF44 was applied in an FC analysis of cells during MDSCs' generation (Eriksson et al., 2019; pmid: 30617223). Another group screened mouce splenocytes with this antibody during tumor studies (Horn et al., 2017; pmid: 28938530). Jardine et al. (2019) utilized this clone to phenotype blood DC cells (pmid: 31040289). Similarly, this antibody was used as a part of a wider panel to phenotype MUTZ-3 and MUTZ-LCs cells (Bock et al., 2016; pmid: 26794428).

Product Class:	Purified
Clone ID:	ICRF44
Synonyms:	Integrin alpha-M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; mAb 44; mAb44
Amount:	200 μg
Application Codes Clone:	FC; IHC; WB; IP
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody recognizes CD11b (Integrin alpha-M) which is an adhesion molecule. CD11b associated with integrin beta2 (CD18) is expressed on the surface of monocytes, granulocytes, activated lymphocytes and a subset of NK cells. CD11b is a receptor for intercellular adhesion molecule family members CD54, CD102 and CD50 as well as for iC3b. These adhesions are crucial in cell-cell and cell-matrix interactions.
Application Notes:	This antibody is recommended for the detection and analysis of CD11b (Integrin alpha-M) and CD11b-plus cells in lineage identification. The original mouse IgG1 format of this clone has been widely used in various flow cytometry experiments. For instance, ICRF44 was applied in an FC analysis of cells during MDSCs' generation (Eriksson et al., 2019; pmid: 30617223). Another group screened mouce splenocytes with this antibody during tumor studies (Horn et al., 2017; pmid: 28938530). Jardine et al. (2019) utilized this clone to phenotype blood DC cells (pmid: 31040289). Similarly, this antibody was used as a part of a wider panel to phenotype MUTZ-3 and MUTZ-LCs cells (Bock et al., 2016; pmid: 26794428).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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