Mfg Part Number
Ab02056-23.0
Vector Labs Ab02056-23.0 Anti-MVEV [M2-8E7], Rabbit IgG, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing BALB/c mice with structural and non structural viral proteins using a crude suspension of infected suckling mouse brain.
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| Product Class: | Purified |
|---|---|
| Clone ID: | M2-8E7 |
| Synonyms: | Murray Valley encephalitis virus; envelope protein; E protein; Japanese encephalitis virus |
| Amount: | 200 μg |
| Application Codes Clone: | NTRL; ELISA; WB; IP |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody reacts with domain III of the envelope protein of the Murray Valley encephalitis virus. The mAb also cross reacts with Japanese encephalitis virus. |
| Application Notes: | This neutralizing antibody binds the the envelope protein of the Murray Valley encephalitis virues in the ectodomain III region. This mAb is reported to block haemagglutination. The competitive binding of the mAb to envelope protein was checked with ELISA (PMID:1703213). Recombinant MVEV E-DIII proteins were detected by M2-8E7 in a western blot assay (PMID: 29083957). This antibody is also reported to be used in immunoprecipitation for the identification of E proteins from cell lysates (PMID: 9770429, 9499070). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |