Mfg Part Number
Ab02077-1.1
Vector Labs Ab02077-1.1 Anti-Gliadin [1E01], Mouse IgG1, lambda (200 μg)
Quick Overview
The original antibody was isolated from the IgA+ plasma cells of celiac patients gut lesions that are reactive with deaminated gluten proteins.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | 1E01 |
| Synonyms: | gluten; Celiac Allergen; Coeliac Allergen |
| Amount: | 200 μg |
| Application Codes Clone: | FC; ELISA; AlphaLISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody can recognize and bind the 'QPEQPFP' peptide of gliadins. This antibody also reacts with deaminated 33mer peptide of α-gliadin 'LQLQPFPQPELPYPQPELPYPQPELPYPQPQPF '. |
| Application Notes: | The binding specificity of IgA+ plasma cells in the single cell suspension was determined by flow cytometry. The relative affinity of the antibody to a panel of gliadin was investigated using ELISA and AlphaLISA (PMID: 27146306, WO2015164615). This antibody recognizes a sequence that intimately associates with deamidation of the gluten peptide. (PMID:28878138). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |