Mfg Part Number
Ab02092-2.0
Vector Labs Ab02092-2.0 Anti-Canine Lymphoma [Mab231], Mouse IgG2a, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing BALB/c mice with cannine lymphoma cell line 17-71.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | Mab231 |
| Synonyms: | Canine Lymphoma 17-71 |
| Amount: | 200 μg |
| Application Codes Clone: | RIA; FC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody binds canine lymphoma cells. |
| Application Notes: | This antibody is recommended for detection of canine lymphoma cells. The binding ability of the hybridoma supernatents with canine lymphoma cells was determined by radioimmunoassay. FACS analysis was used to analyse the binding of the antibody to cells freshly isolated from canine lymphomatous nodes and normal lymphocytes of canine and human blood (Steplewski et al., 1987). This antibody has been shown to exhibit antibody-dependent cellular cytotoxicity as well as complement-dependant cytolysis (Rosales et al., 1988). Canine lymphoma is conventionally treated with chemotherapy, but it was found that subsequent treatment with a specific monoclonal antibody, Mab 231, raised against the lymphoma, substantially prolonged remission and survival times (Jeglum, 1989). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |