Mfg Part Number
Ab02097-201.1
Vector Labs Ab02097-201.1 Anti-Rabies Virus Glycoprotein [R16E5], Dog IgG2 (IgG-B), lambda (200 μg)
Quick Overview
The original antibody was generated from a heterohybridoma which was developed by fusing primary immune peripheral blood B-cells and a heteromyeloma cell line, K6H6/B5 and screening them against inactivated rabies virus antigen.
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| Product Class: | Purified |
|---|---|
| Clone ID: | R16E5 |
| Synonyms: | PV GP; PV; RABV; Site III; Glycoprotein; Rabies virus; strain Pasteur vaccins; Lyssavirus |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; WB; NTRL |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric dog antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody recognizes and binds the antigenic site III of the rabies virus glycoprotein. However, it is not capable of binding the CVS-BHK strain of the rabies virus. |
| Application Notes: | This antibody successfully binds and neutralizes the rabies virus glycoprotein of the PV, CVS-11, SAD and Flury LEP strains. It does not bind the CVS-BHK strain. The binding specificity of the antibody for rabies virus glycoprotein was confirmed with ELISA and western blotting. This antibody in combination with another murine anti-rabies antibody M5B4 was used in the preparation of a diabody D06 (PMID: 20573881). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |