Mfg Part Number
Ab02113-1.1
Vector Labs Ab02113-1.1 Anti-Pan-Nav channel [K58/35], Mouse IgG1, kappa (200 μg)
Quick Overview
This antibody was raised by immunising mice with a synthetic peptide corresponding to a highly conserved segment of the intracellular III–IV loop of vertebrate Na+ channels.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | K58/35 |
| Synonyms: | K58/35R; sodium voltage-gated channel; Na+ channel |
| Amount: | 200 μg |
| Application Codes Clone: | IB; WB; IHC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This pan-voltage-gated sodium channel antibody is specific for a conserved sequence present in all vertebrate Nav1 isoforms. It binds to all voltage-gated sodium channel isoforms. |
| Application Notes: | This antibody has been used to stain teased axons prepared from rat spinal nerves (Devaux, 2012), sections of rat retina (Wart et al, 2005) and mice optic nerve cryosections (Vega et al, 2008) for Nav expression. This antibody has been shown to label Nav channels concentrated on the axon initial segment and nodes of Ranvier (Andrews et al, 2019). This antibody has been used in immunoblot analysis of rat brain membranes (Wart et al, 2005; Vega et al, 2013), and to stain COS-1 cells transfected with Nav1 cDNA (Wart et al, 2005). Additionally, this antibody has been used in western blot analysis of mice optic nerve and brain membrane proteins (Vega et al, 2008). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |