Mfg Part Number
Ab02128-8.1

Vector Labs Ab02128-8.1 Anti-HCN4 [N114/10.1], Rat IgG2b, kappa (200 μg)

Quick Overview
This antibody was raised by immunising BALB/c mice a fusion protein of GST and amino acids 1019 to 1108 of rat HCN4.
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Product Class:Purified
Clone ID:N114/10.1
Synonyms:N114/10.1R; Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; brain cyclic nucleotide-gated channel 3; N114/10
Amount:200 μg
Application Codes Clone:IF; IHC; WB; IP
Shipping Temperature:Wet Ice
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG1
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:This antibody is specific for the HCN4 antigen. This is a hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions.
Application Notes:The antibody was used in immunofluorescense on the spinal motor neurons and the hippocampus of rats (Hughes et al, 2013; PMID:23357121) (Khurana et al, 2012; PMID:22357864). Immunohistochemistry has been preformed using this antibody on the retinas of rats (Partida et al, 2012; PMID:22281825). Western blot has been preformed on lysate made from rat retinas using this antobody (Partida et al, 2012; PMID:22281825). This antibody can be used for immunopercipitation on rat retinas (Partida et al, 2012; PMID:22281825).
More Information
Brand Vector Labs
UNSPSC 12161500