Mfg Part Number
Ab02141-8.4
Vector Labs Ab02141-8.4 Anti-Navbeta4 Na+ channel [N168/6.3], Rat IgG2b, Fc Silent™, kappa (200 μg)
Quick Overview
This antibody was raised by immunising BALB/c mice with a fusion protein amino acids 184-228 (cytoplasmic C-terminus) of rat Navbeta4.
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| Product Class: | Purified |
|---|---|
| Clone ID: | N168/6.3 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | N168/6.3R; N168/6; Sodium channel subunit beta-4; Scn4b; Navbeta4 |
| Amount: | 200 μg |
| Application Codes Clone: | ICC; IHC; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for the Navbeta4 protein in mice and rats. This protein Modulates channel gating kinetics. |
| Application Notes: | This antibody is recommended for the detection and analysis of Navbeta4 Na+ channel by immunocytochemistry, western blot and immunohistochemistry. For instance, the mouse version of this antibody was used to detect Navbeta4 Na+ channel by western blot in extracts of RBM and COS cells transiently transfected with GFP-tagged Navbeta4 or untagged Kv2.1 plasmid. Furthermore it was used to detect Navbeta4 Na+ channel by immunocytochemistry in adult rat sciatic nerves. And finally it was also used for detection of Navbeta4 Na+ channel by immunohistochemistry in adult rat brain. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |