Mfg Part Number
Ab02149-23.0
Vector Labs Ab02149-23.0 Anti-PARIS/ZNF746 [N196/16], Rabbit IgG, kappa (200 μg)
Quick Overview
This antibody was raised by immunising BALB/c mice with a fusion protein amino acids 1-322 (N-terminus) of human ZNF746.
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| Product Class: | Purified |
|---|---|
| Clone ID: | N196/16 |
| Synonyms: | N196/16R; Zinc finger protein 746; ZNF746; Parkin-interacting substrate; PARIS |
| Amount: | 200 μg |
| Application Codes Clone: | WB; IHC; IP |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for the PARIS/ZNF746 protein. The antibody does not cross-react with ZNF783 or ZNF398. ZNF746 is a transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death. |
| Application Notes: | Western blot was preformed on mouse lung tissue using this antibody (Zhang et al, 2014; PMID:24778451). This antibody was used for immunohistochemistry on mouse brains (Brahmachari et al, 2019; PMID:31237944). The antibody was used in the immunopercipitation of proteins from the brain of a mouse (Brahmachari et al, 2019; PMID:31237944). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |