Mfg Part Number
Ab02156-23.0

Vector Labs Ab02156-23.0 Anti-MMACHC [N230/21], Rabbit IgG, kappa (200 μg)

Quick Overview
This antibody was raised by immunising BALB/c mice with a fusion protein amino acids 1-282 (full-length) of human MMACHC.
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Product Class:Purified
Clone ID:N230/21
Synonyms:N230/21R; Cyanocobalamin reductase / alkylcobalamin dealkylase; Alkylcobalamin:glutathione S-alkyltransferase; CblC; Cyanocobalamin reductase (cyanide-eliminating); Methylmalonic aciduria and homocystinuria type C protein
Amount:200 μg
Application Codes Clone:WB
Shipping Temperature:Wet Ice
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG1
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:This antibody is specific for the MMACHC protein. MMACHC is a cobalamin (vitamin B12) cytosolic chaperone that catalyzes the reductive decyanation of cyanocob(III)alamin (cyanocobalamin, CNCbl) to yield cob(II)alamin and cyanide, using FAD or FMN as cofactors and NADPH as cosubstrate.
Application Notes:This antibody was used to preform a western blot on lysated mouse embryos (Moreno-Garcia et al, 2014; PMID:24889031).
More Information
Brand Vector Labs
UNSPSC 12161500