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Mfg Part Number

Ab02158-8.4

Vector Labs Ab02158-8.4 Anti-Pan-Shank Pan [N23B/49], Rat IgG2b, Fc Silent™, kappa (200 μg)

VECTOR LABS

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Quick Overview

This antibody was raised by immunising BALB/c mice with a fusion protein amino acids 84-309 (SH3/PDZ domains) of rat Shank2.

$517.40

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Description

Product Class: Purified
Clone ID: N23B/49
Heavy Chain Modification: Fc Silent™
Synonyms: N23B/49R; SH3 and multiple ankyrin repeat domains protein 2; Cortactin-binding protein 1; CortBP1; GKAP/SAPAP-interacting protein; Proline-rich synapse-associated protein 1; ProSAP1; SPANK-3
Amount: 200 μg
Application Codes Clone: ICC; WB; IF
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody is specific for shank1, shank2 and shank3. Shank2 seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.
Application Notes: This antibody was used for immunocytochemistry on the hippocampal cultures of rats and mice (MacGillavry et al, 2016; PMID:26547831) (Tao-Cheng et al, 2010; PMID:20347015) (Suh et al, 2010; PMID:20118925). Immunofluorescense was preformed on hippocampal neuronal cells of mice using this anitbody (Pham et al, 2010; PMID:20573181) (Ricciardi et al, 2012; PMID:22922712). This antibody was used to preform a western blot on human brain samples (Pham et al, 2010; PMID:20573181).

Product Class:	Purified
Clone ID:	N23B/49
Heavy Chain Modification:	Fc Silent™
Synonyms:	N23B/49R; SH3 and multiple ankyrin repeat domains protein 2; Cortactin-binding protein 1; CortBP1; GKAP/SAPAP-interacting protein; Proline-rich synapse-associated protein 1; ProSAP1; SPANK-3
Amount:	200 μg
Application Codes Clone:	ICC; WB; IF
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody is specific for shank1, shank2 and shank3. Shank2 seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.
Application Notes:	This antibody was used for immunocytochemistry on the hippocampal cultures of rats and mice (MacGillavry et al, 2016; PMID:26547831) (Tao-Cheng et al, 2010; PMID:20347015) (Suh et al, 2010; PMID:20118925). Immunofluorescense was preformed on hippocampal neuronal cells of mice using this anitbody (Pham et al, 2010; PMID:20573181) (Ricciardi et al, 2012; PMID:22922712). This antibody was used to preform a western blot on human brain samples (Pham et al, 2010; PMID:20573181).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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