Mfg Part Number
Ab02162-8.1
Vector Labs Ab02162-8.1 Anti-Synaptotagmin-12 [N277/7], Rat IgG2b, kappa (200 μg)
Quick Overview
This antibody was raised by immunising BALB/c mice with a fusion protein amino acids 168-255 (cytoplasmic C2A domain) of mouse Synaptotagmin-12
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| Product Class: | Purified |
|---|---|
| Clone ID: | N277/7 |
| Synonyms: | N277/7R; Syt12; Synaptotagmin XII; SytXII |
| Amount: | 200 μg |
| Application Codes Clone: | ICC; IHC; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for the synaptotagmin-12 protein. The antibody does not cross-react with Synaptotagmin-6 (or other Synaptotagmins). Synaptotagmin-12 is a synaptic vesicle phosphoprotein that enhances spontaneous neurotransmitter release but does not effect induced neurotransmitter release (By similarity). Unlike other synaptotagmins, it does not bind Ca2+ or phospholipids (By similarity). |
| Application Notes: | This antibody is recommended for the detection and analysis of Synaptotagmin-12 by immunocytochemistry, immunohistochemistry and western blot. For instance, the mouse version of this antibody was used to detect Synaptotagmin-12 by western blot in extracts of COS cells transiently transfected with GFP-tagged Synaptotagmin plasmid. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |