Mfg Part Number
Ab02183-8.4
Vector Labs Ab02183-8.4 Anti-Pan-Nav1 Na+ channel [N419/40], Rat IgG2b, Fc Silent™, kappa (200 μg)
Quick Overview
This antibody was raised by immunising BALB/c mice with a synthetic peptide amino acids 1501-1518 (TEEQKKYYNAMKKLGSKK, cytoplasmic loop between repeat III and IV) of human Nav1.1.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | N419/40 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | N419/40R; Sodium channel protein type 1 subunit alpha; Sodium channel protein brain I subunit alpha; Sodium channel protein type I subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.1; SCN1A |
| Amount: | 200 μg |
| Application Codes Clone: | WB; ICC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds to most Nav1 channels. Nav1 channels mediate the voltage-dependent sodium ion permeability of excitable membranes. |
| Application Notes: | This antibody was used for western blotting on adult rat brains (Gong et al, 2016; PMID:26644354). Immunocytochemistry on rat neurons was preformed with this antibody (Hefting et al, 2020; PMID:32116557) (Solé et al, 2019; PMID:30914445). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |