Mfg Part Number
Ab02184-10.3

Vector Labs Ab02184-10.3 Anti-Pan-Nav1 Na+ channel [N419/78], Human IgG1, Fc Silent™, kappa (200 μg)

Quick Overview
This antibody was raised by immunising BALB/c mice with a synthetic peptide amino acids 1501-1518 (TEEQKKYYNAMKKLGSKK, cytoplasmic loop between repeat III and IV) of human Nav1.1.
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Product Class:Purified
Clone ID:N419/78
Heavy Chain Modification:Fc Silent™
Synonyms:N419/78R; Sodium channel protein type 1 subunit alpha; Sodium channel protein brain I subunit alpha; Sodium channel protein type I subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.1; SCN1A
Amount:200 μg
Application Codes Clone:ICC; IHC; WB
Shipping Temperature:Wet Ice
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG2a
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:This antibody binds to most Nav1 channels. Nav1 channels mediate the voltage-dependent sodium ion permeability of excitable membranes.
Application Notes:This antibody is recommended for detection and analysis of Nav1 Na+ channel by immunocytochemistry, immunohistochemistry and western blot. For instance, the mouse version of this antibody was used to detect nav1 Na+ channel by western blot in fractions of adult rat brain membranes and extracts of COS or HEK cells transiently or stably expressing different untagged Nav1.X or Kv2.1 plasmid.
More Information
Brand Vector Labs
UNSPSC 12161500