Mfg Part Number
Ab02203-30.11
Vector Labs Ab02203-30.11 Anti-HA [AV.C4], scFv fragment (His), ScFv, (50 μg)
Quick Overview
The original antibody was isolated from human semi-synthetic ETH-2 phage antibody library by biopanning against H5 hemagglutinin.
$692.90
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| Product Class: | Purified |
|---|---|
| Clone ID: | AV.C4 |
| Heavy Chain Modification: | ScFv |
| Synonyms: | Hemagglutinin; Avian Influenza Virus; AIV; H5N1; H5N2; H5N3; Influenza A virus |
| Amount: | 50 μg |
| Application Codes Clone: | NTRL; ELISA; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody binds the hemaglutinin of the H5N1 avian influenza virus. |
| Application Notes: | The specificity of this scFv antibody for binding H5 type of hemaglutinin was determined by ELISA. AV.C4 binds a conserved epitope shared by three different virus strains belonging to the H5 subtype, i.e. the homologous strain A/Vietnam/ 1194/04 (H5N1), and two viruses isolated form wild birds, A/Nammalr/Italy/80/93 (H5N2) and A/Mallard/Italy/208/00 (H5N3). This antibody does not cross react with H1N1 influenza virus. scFv clone AV.C4 exerted a significant inhibition of the H5N1 A/Vietnam/1194/2004 virus infection in a pseudotype-based neutralization assay. This antibody was capable of detecting a 70kDa protein corresponding to the uncleaved HA protein in a western blot assay (PMID: 19481117). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |