Mfg Part Number
Ab02209-10.3
Vector Labs Ab02209-10.3 Anti-CD56 [N901], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing mice with human chronic myelogenous leukemia (CML) cells.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | N901 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | NCAM1; NCAM; NCAM-1; Neural cell adhesion molecule 1 |
| Amount: | 200 μg |
| Application Codes Clone: | IP; IF; FC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds CD56, present on large granular lymphocytes including natural killer cells. This antibody does not react with monocytes, granulocytes, B cells, erythrocytes, or platelets. |
| Application Notes: | This antibody does not block the natural killer cell activity and can be used to rapidly purify functional NK cells (PMID:6574190). This antibody was able to precipitate a band at approx. 200-250 kdalton protein in a immunoprecipitation assay. This antibody successfully blocked the binding of anti-NKH1A antibody in an indirect immunofluorescence assay (PMID:3884668). This antibody is also recommended to be used in the study of cell surface antigens of the natural cells (PMID: 3875369). Conjugate of DC1 with murine and humanizsed versions of N901 was found to be potent and effective in selective killing of target cells in culture (PMID: 7545085). THis antibody can also be used for the separation of natural killer cells in a flow cytometry (PMID: 15985539). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |