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Mfg Part Number

Ab02229-10.3

Vector Labs Ab02229-10.3 Anti-CD80 [B7-24], Human IgG1, Fc Silent™, kappa (200 μg)

VECTOR LABS

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Quick Overview

The original antibody was generated by fusion with splenocytes from a mouse immunized with Sf9 insect cells expressing the human B7 molecule.

$517.40

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Description

Product Class: Purified
Clone ID: B7-24
Heavy Chain Modification: Fc Silent™
Synonyms: BB1; B7; B7-1; B7.1; CD28LG; CD28LG1; LAB7; Activation B7-1 antigen; T-lymphocyte activation antigen CD80; CTLA-4 counter-receptor B7.1; B-lymphocyte activation antigen B7; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); costimulatory factor CD80; costimulatory molecule variant IgV-CD80 ; CTLA4L; CTLA-4L
Amount: 200 μg
Application Codes Clone: FC; IP; IHC
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG2a
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This monoclonal antibody recognizes human CD80 expressed on human blood dendritic cells and on in vitro activated (but not resting) B cells and monocytes.
Application Notes: This mAb binds to a functionally important epitope of the B7 molecule. B7-24 is not able to inhibit T cell proliferation in primary mixed lymphocyte reactions where purified T cells are co-cultured with Epstein-Barr virus-transformed B cells. This antibody was used to study the cell surface expression of B7 antigen using flow cytometry. This antibody was also able to immunoprecipitate radioactive Iodine-labeled EBV-transformed B cells (PMID: 1280221). This antibody was used to examine the in situ expression of B7/BB1 by immunohistochemistry (PMID: 7682106).

Product Class:	Purified
Clone ID:	B7-24
Heavy Chain Modification:	Fc Silent™
Synonyms:	BB1; B7; B7-1; B7.1; CD28LG; CD28LG1; LAB7; Activation B7-1 antigen; T-lymphocyte activation antigen CD80; CTLA-4 counter-receptor B7.1; B-lymphocyte activation antigen B7; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); costimulatory factor CD80; costimulatory molecule variant IgV-CD80 ; CTLA4L; CTLA-4L
Amount:	200 μg
Application Codes Clone:	FC; IP; IHC
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG2a
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This monoclonal antibody recognizes human CD80 expressed on human blood dendritic cells and on in vitro activated (but not resting) B cells and monocytes.
Application Notes:	This mAb binds to a functionally important epitope of the B7 molecule. B7-24 is not able to inhibit T cell proliferation in primary mixed lymphocyte reactions where purified T cells are co-cultured with Epstein-Barr virus-transformed B cells. This antibody was used to study the cell surface expression of B7 antigen using flow cytometry. This antibody was also able to immunoprecipitate radioactive Iodine-labeled EBV-transformed B cells (PMID: 1280221). This antibody was used to examine the in situ expression of B7/BB1 by immunohistochemistry (PMID: 7682106).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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