Mfg Part Number
Ab02249-8.1
Vector Labs Ab02249-8.1 Anti-GluN2B/NR2B glutamate receptor [N59/36.1], Rat IgG2b, kappa (200 μg)
Quick Overview
This antibody was raised by immunising BALB/c mice with a fusion of protein amino acids 20-271 (extracellular N-terminus) of rat NR2B.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | N59/36.1 |
| Synonyms: | N59/36.1R; GluN2B; Glutamate receptor ionotropic, NMDA 2B; Glutamate [NMDA] receptor subunit epsilon-2; N-methyl D-aspartate receptor subtype 2B; NMDAR2B; NR2B |
| Amount: | 200 μg |
| Application Codes Clone: | WB; IP; ICC; IF; IHC; KO |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for the NR2B protein, a component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. |
| Application Notes: | The IgG2a version of this antibody has been used in western blotting on rat cortical neurons (Plowey et al, 2014; PMID: 24874075). Co-immunoprecipitation has been preformed on extrasynaptic membranes of adult rat brains with the IgG2A version of this antibody (Chiu et al, 2019; PMID:31291571). This antibody has shown use in immunocytochemistry, immunofluorescence, immunohistochemistry or for knock out. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |