Mfg Part Number
Ab02252-23.0

Vector Labs Ab02252-23.0 Anti-Ataxin-1, 11NQ [N76/3], Rabbit IgG, kappa (200 μg)

Quick Overview
This antibody was raised by immunising BALB/c mice with a fusion protein amino acids 778-910 (cytoplasmic C-terminus) of rat HCN1.
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Product Class:Purified
Clone ID:N76/3
Synonyms:N76/3R; Atxn1; Spinocerebellar ataxia type 1 protein homolog; Ataxin-1
Amount:200 μg
Application Codes Clone:WB; IHC; IF
Shipping Temperature:Wet Ice
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG2a
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:This antibody is specific for amino acids 778-910 of HCN1. It shows no cross-reactivity against HCN2. HCN1 is a chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor.
Application Notes:This antibody has been used in western blot on the brain of a mouse (Hu et al, 2019; PMID:30649233). Immunohistrochemistry on the brain of a mouse has been preformed with this antibody (Hu et al, 2019; PMID:30649233). The antibody has shown use in immunofluorescence experiments on neurospheres, differentiates cells and cerebral tissues of mice (Edamakanti et al, 2018; PMID:29533923).
More Information
Brand Vector Labs
UNSPSC 12161500