JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

Skip to the beginning of the images gallery

Mfg Part Number

Ab02260-8.4

Vector Labs Ab02260-8.4 Anti-GABA(B)R [N93A/49.2], Rat IgG2b, Fc Silent™, kappa (200 μg)

VECTOR LABS

Be the first to review this product

Quick Overview

This antibody was raised by immunising BALB/c mice with a fusion protein of amino acids 873-977 (cytoplasmic C-terminus) of rat GABABR1.

$517.40

Order will ship within 1-3 business days

Description

Product Class: Purified
Clone ID: N93A/49.2
Heavy Chain Modification: Fc Silent™
Synonyms: N93A/49.2R; Gamma-aminobutyric acid type B receptor subunit 1; Gabbr1; GABA-B receptor 1; GABA-B-R1; GABA-BR1; GABABR1; Gb1
Amount: 200 μg
Application Codes Clone: PLA; IP; IF
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG2a
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody is specific for amino acids 873-977 (cytoplasmic C-terminus) of rat GABABR1. GABABR1 is a component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins.
Application Notes: This antibody was used in a proximity ligation assay on HEK293 cells transiently transfected using Lipofectamine 2000 with cDNA plasmids expressing GABABR1-eYFP, GABABR2 and GIRK2a (Li et al, 2020; PMID:32111696). Immunofluorescence was preformed on the hippocampal slices of P7 male Wistar rats using this antibody (Wright et al, 2017; PMID:28450542). An immunoprecipitation was preformed with this antibody on lysates from hippocampal slices of P7 male Wistar rats (Wright et al, 2017; PMID:28450542). Immunofluorescence was preformed on the brain of Tg(Gng3-GFP)- HK208Gsat and KI(Gng7-3-IRES-GFP) mice (Schwindinger et al, 2012; PMID:22207761).

Product Class:	Purified
Clone ID:	N93A/49.2
Heavy Chain Modification:	Fc Silent™
Synonyms:	N93A/49.2R; Gamma-aminobutyric acid type B receptor subunit 1; Gabbr1; GABA-B receptor 1; GABA-B-R1; GABA-BR1; GABABR1; Gb1
Amount:	200 μg
Application Codes Clone:	PLA; IP; IF
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG2a
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody is specific for amino acids 873-977 (cytoplasmic C-terminus) of rat GABABR1. GABABR1 is a component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins.
Application Notes:	This antibody was used in a proximity ligation assay on HEK293 cells transiently transfected using Lipofectamine 2000 with cDNA plasmids expressing GABABR1-eYFP, GABABR2 and GIRK2a (Li et al, 2020; PMID:32111696). Immunofluorescence was preformed on the hippocampal slices of P7 male Wistar rats using this antibody (Wright et al, 2017; PMID:28450542). An immunoprecipitation was preformed with this antibody on lysates from hippocampal slices of P7 male Wistar rats (Wright et al, 2017; PMID:28450542). Immunofluorescence was preformed on the brain of Tg(Gng3-GFP)- HK208Gsat and KI(Gng7-3-IRES-GFP) mice (Schwindinger et al, 2012; PMID:22207761).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

Reviews