Mfg Part Number
Ab02283-8.4
Vector Labs Ab02283-8.4 Anti-Cavbeta2 Ca2+ channel [N8B/1R], Rat IgG2b, Fc Silent™, kappa (200 μg)
Quick Overview
This antibody was raised by immunizing a mouse with the rat Cavbeta2 Ca2+ channel antigen.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | N8B/1R |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | Calcium channel voltage-dependent subunit beta 2; Cacnb2; Voltage-dependent L-type calcium channel subunit beta-2; N8B/1 |
| Amount: | 200 μg |
| Application Codes Clone: | IF |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for the Cavbeta2 Ca2+ channel antigen. It does not cross-react with Cavβ1, Cavβ3, Cavβ4. The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. |
| Application Notes: | Immunofluorescence was preformed with this antibody on neurons from mice (Held et al, 2020; PMID:32616470). This antibody was used for immunofluorescence on rat neurons (Ortiz-miranda et al, 2010; PMID:20509142). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |