Mfg Part Number
Ab02317-8.4
Vector Labs Ab02317-8.4 Anti-Snapin/SNAPAP [L8/15R], Rat IgG2b, Fc Silent™, kappa (200 μg)
Quick Overview
This antibody was raised against a synthetic peptide of amino acids 115-136 of human snapin.
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| Product Class: | Purified |
|---|---|
| Clone ID: | L8/15R |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | SNARE-associated protein Snapin; SNAPIN; Biogenesis of lysosome-related organelles complex 1 subunit 7; BLOC-1 subunit 7; Synaptosomal-associated protein 25-binding protein; SNAP-associated protein; L8/15 |
| Amount: | 200 μg |
| Application Codes Clone: | ICC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for Snapin. Snapin is a component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. |
| Application Notes: | Immunocytochemistry was preformed on neurones or mouse N11 cells cultured on poly-L-lysinecoated coverslips with this antibody (Makani et al, 2013; PMID:24118254). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |