Mfg Part Number
Ab02344-2.0
Vector Labs Ab02344-2.0 Anti-Ft OAg [N203 ], Mouse IgG2a, kappa (200 μg)
Quick Overview
The original antibody was generated by intradermal immunization of BALB/cJ mice with sub-lethal dose of Francisella tularensis holarctica strain LVS followed by intraperitoneal booster immunization with an outer membrane- or capsule-enriched LVS preparation.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | N203 |
| Synonyms: | O-antigen of Francisella tularensis; O-antigen ligase family protein |
| Amount: | 200 μg |
| Application Codes Clone: | WB, ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody binds the internal O-antigen (OAg) of the gram-negative bacterium Francisella tularensis (Ft). |
| Application Notes: | This antibody is recommended for the detection of the O anitgen of F. tularensis through ELISA. It is reported to react with high molecular weight F. tularensis lipopolysaccharide chains in a western bloy assay. In a mouse model of respiratory tularemia with the highly virulent Ft type A strain SchuS4, this antibody reduced blood bacterial burden with potencies that mirror its antigen-binding strength. N203 prolonged survival in a dose dependent manner. This clone is a less potent binder than Ab52 (PMID: 25171003). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |