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Mfg Part Number

Ab02351-1.4

Vector Labs Ab02351-1.4 Anti-CD142 [10H10 (TF9-10H10)], Mouse IgG1, Fc Silent™, kappa (200 μg)

VECTOR LABS

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Quick Overview

The original antibody was generated by subcutaneously immunizing a mouse with denatured human TF protein in R-700 adjuvant.

$517.40

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Description

Product Class: Purified
Clone ID: 10H10 (TF9-10H10)
Heavy Chain Modification: Fc Silent™
Synonyms: TF; F3; Tissue factor; Coagulation factor III; Thromboplastin
Amount: 200 μg
Application Codes Clone: ELISA, IF, IHC
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Specificity Statement: This antibody binds the human tissue factor heavy chain protein (huTFh) and specifically binds huTFh polypeptide p1-30.
Application Notes: Tissue factor (TF), one of the cell-surface initiators of blood coagulation and has been identified as a critical controlling molecule in hemostasis, thrombosis and inflammation. This antibody is recommended for detection of tissue factor in a blood sample. This is a non neutralizing antibody, which is capable of binding human tissue factor heavy chain protein but does not neutralize the ability of tissue factor to initiate coagulation. This antibody was used to study the interaction between factor VII and tissue factor in solution using ELISA (PMID: 1874730). This antibody is also reported to be used to target TF pathway as a possible treatment strategy for glioblastoma therapy (PMID: 23384223). This antibody was used to study expression of TF in human glioma using immunofluorescence staining for identification of TF in U251 glioma cell line, normal brain specimens, and glioma surgical specimens (PMID: 12135696). This antibody was also used in the detection of TF in normal and abnormal human mammary glands using immunohistochemistry (PMID: 1514249).

Product Class:	Purified
Clone ID:	10H10 (TF9-10H10)
Heavy Chain Modification:	Fc Silent™
Synonyms:	TF; F3; Tissue factor; Coagulation factor III; Thromboplastin
Amount:	200 μg
Application Codes Clone:	ELISA, IF, IHC
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Specificity Statement:	This antibody binds the human tissue factor heavy chain protein (huTFh) and specifically binds huTFh polypeptide p1-30.
Application Notes:	Tissue factor (TF), one of the cell-surface initiators of blood coagulation and has been identified as a critical controlling molecule in hemostasis, thrombosis and inflammation. This antibody is recommended for detection of tissue factor in a blood sample. This is a non neutralizing antibody, which is capable of binding human tissue factor heavy chain protein but does not neutralize the ability of tissue factor to initiate coagulation. This antibody was used to study the interaction between factor VII and tissue factor in solution using ELISA (PMID: 1874730). This antibody is also reported to be used to target TF pathway as a possible treatment strategy for glioblastoma therapy (PMID: 23384223). This antibody was used to study expression of TF in human glioma using immunofluorescence staining for identification of TF in U251 glioma cell line, normal brain specimens, and glioma surgical specimens (PMID: 12135696). This antibody was also used in the detection of TF in normal and abnormal human mammary glands using immunohistochemistry (PMID: 1514249).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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