Mfg Part Number
Ab02386-23.0

Vector Labs Ab02386-23.0 Anti-3-pHis [SC56-2], Rabbit IgG, kappa (200 μg)

Quick Overview
The original rabbit version of this antibody was raised by immunizing rabbits with a 3-pTza library conjugated to the carrier protein keyhole limpet hemocyanin (KLH).
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Product Class:Purified
Clone ID:SC56-2
Synonyms:3-phosphohistidine; N3-Phosphohistidine; histidine
Amount:200 μg
Application Codes Clone:IAC; WB; IF; ELISA
Shipping Temperature:Wet Ice
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Specificity Statement:This antibody is specific for 3-pHis and does not cross react with phosphotyrosine (pTyr) or the other pHis isomers.
Application Notes:This antibody can be used for the identification of 3-pHis substrates and functional study of pHis. It was used in an immunoblot performed on four recombinant HK proteins—EnvZ, WalK, ArcB, and EvgS (Kinoshita-Kikuta et al, 2020; pmid:32360198). SC56-2 was also used in Western blot analyses on NDPK-B and PGAM5 proteins (Panda et al, 2016; pmid:27453048) and on mouse liver tissue as well as LX-2 cells (Gong et al, 2020; pmid:32860079). Furthermore, immunoaffinity purification was preformed using this antibody on SK-N-BE(2) xenograft tumors from mice (Adam et al, 2020; pmid:32392889). This clone was also utilized in the immunofluorescence staining (Yang et al, 2019; pmid:31721359). Finally, an ELISA was preformed on 3-day differentiated Sca1+-VPCs with this antibody (Yang et al, 2019; pmid:31721359).
More Information
Brand Vector Labs
UNSPSC 12161500