Mfg Part Number
Ab02391-3.0
Vector Labs Ab02391-3.0 Anti-Amyloid Beta [21F12], Mouse IgG2b, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing A/J mice with a synthetic peptide (NH2-CYS-NH-CH2-(CH2)5-CO-GLMVGGVVIA-COOH) as an immunogen.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 21F12 |
| Synonyms: | Abeta; A-beta; Aβ; Aβ42; Alzheimer disease amyloid protein; S-APP-beta |
| Amount: | 200 μg |
| Application Codes Clone: | IP; ELISA; WB; IHC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2b |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody recognizes amino acids 33-42 of amyloid beta. |
| Application Notes: | This antibody has very high specificity for Aβ1–42 over Aβ1–40. This antibody is capable of immunoprecipitating Aβ peptides ending at aa position 42 and also p3 peptides (PMID: 8917563). This antibody is also recomended for detection of amyloid beta using sandwich ELISA (PMID: 9037091, 19204155). This antibody was also used in the quantification of the proportion of full-length Aβ using western blotting (PMID: 12787077). This antibody has also been used for the identification of Aβ42 plaques on paraffin frontal sections(PMID: 15215183, 19660650). This antibody is unable to bind plaques in unfixed brain sections. This antibody is also not capable of clearing plaque after in vivo administration (PMID: 10932230). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |