Vector Labs Ab02547-10.0 Anti-Sodium-dependent serotonin transporter [1-4A5], Human IgG1, kappa (200 μg) Centrifuge Bundle Savings at Sycamore Life Sciences

Description

Product Class: Purified
Clone ID: 1-4A5
Synonyms: SLC6A4; SERT; 5HT transporter; 5HTT; Solute carrier family 6 member 4
Amount: 200 μg
Application Codes Clone: IHC; IF; WB; ICC
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody is specific for the sodium-dependent serotonin transporter. This protein is a serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
Application Notes: This antibody was used for immunohistochemistry on monkey midbrain and hypothalamic sections (Lu et al, 2003; pmid:12660809). Immunofluorescence was preformed on rat neurons using this antibody (Wersinger and Sidhu, 2009; pmid:19429025). SERT protein was analyzed with a western blot using this antibody (Chamba et al, 2008; pmid:18783838). Immunocytochemistry was preformed on stable Bcl-2 transfectants of EBV-ve L3055 Burkitt's lymphoma cells with this antibody (Chamba et al, 2008; pmid:18783838). This antibody was used for immunohistochemistry on mouse brain sections (Zhu et al, 2011; pmid:21705486). Pellets from the centrifuged homogenized rhesus monkey midbrain pontine blocks containing membrane-bound proteins were immonublotted with this antibody (Smith et al, 2004; pmid:15199371). Western blot was preformed on a human colon adenocarcinoma Caco-2 cell line using this antibody (Mastrangelo et al, 2008; pmid:18593952).

Product Class:	Purified
Clone ID:	1-4A5
Synonyms:	SLC6A4; SERT; 5HT transporter; 5HTT; Solute carrier family 6 member 4
Amount:	200 μg
Application Codes Clone:	IHC; IF; WB; ICC
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody is specific for the sodium-dependent serotonin transporter. This protein is a serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
Application Notes:	This antibody was used for immunohistochemistry on monkey midbrain and hypothalamic sections (Lu et al, 2003; pmid:12660809). Immunofluorescence was preformed on rat neurons using this antibody (Wersinger and Sidhu, 2009; pmid:19429025). SERT protein was analyzed with a western blot using this antibody (Chamba et al, 2008; pmid:18783838). Immunocytochemistry was preformed on stable Bcl-2 transfectants of EBV-ve L3055 Burkitt's lymphoma cells with this antibody (Chamba et al, 2008; pmid:18783838). This antibody was used for immunohistochemistry on mouse brain sections (Zhu et al, 2011; pmid:21705486). Pellets from the centrifuged homogenized rhesus monkey midbrain pontine blocks containing membrane-bound proteins were immonublotted with this antibody (Smith et al, 2004; pmid:15199371). Western blot was preformed on a human colon adenocarcinoma Caco-2 cell line using this antibody (Mastrangelo et al, 2008; pmid:18593952).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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