Vector Labs Ab02548-23.0 Anti-Sodium-dependent noradrenaline transporter [2-3B2], Rabbit IgG, kappa (200 μg) Centrifuge Bundle Savings at Sycamore Life Sciences

Description

Product Class: Purified
Clone ID: 2-3B2
Synonyms: Slc6a2; Norepinephrine transporter; NET; Solute carrier family 6 member 2
Amount: 200 μg
Application Codes Clone: WB; IHC; IP; ICC; IF
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody is specific for the sodium-dependent noradrenaline transporter. This antibody is an amine transporter. Terminates the action of noradrenaline by its high-affinity sodium-dependent reuptake into presynaptic terminals.
Application Notes: Striatum tissues from 2- and 8-month-old wild-type and transgenic mice were immunoblotted using this antibody (Graham and Sidhu, 2010; PMID: 20077428). Freshly dissected mouse brain tissues were immunoblotted using this antibody (Ye et al., 2015; PMID: 26793096). This antibody was used for immunoblotting on protein from the mesenteric PVAT, mesenteric resistance vessels, adipocytes, SVF, and vena cava. The test animal used was a rat (Ayala-Lopez et al., 2015; PMID: 26432838). Mouse NET protein was immunoprecipitated using this antibody (Mannangatti et al., 2015; PMID: 25724654). Mouse NET protein was immunoblotted using this antibody (Mannangatti et al., 2015; PMID: 25724654). An immunoblot was performed on proteins from NET knockout mice using this antibody (Fentress et al., 2013; PMID: 24102798). Alvarial osteoblasts isolated from 3–4-day-old neonatal mice were immunoblotted using this antibody (Ma et al., 2013; PMID: 24005671). Immunocytochemistry was performed in formalin-fixed long bones of neonatal mice using this antibody (Ma et al., 2013; PMID: 24005671). Brain tissue from mice homozygous for a mutant human A53T-α-Syn transgene driven by the prion promoter (A53T) was immunoblotted with this antibody (Oaks et al., 2013; PMID: 23560093). Proteins from knock-in mice carrying the NET A457P allele were immunoblotted with this antibody (Shirley-Rice et al., 2013; PMID: 23580201). In a study investigating the role of the sodium-dependent vitamin C transporter-2 (SVCT2) in transporting VC at the cortical nerve terminal, this antibody was used for immunostaining on cultured SCG neurons (Pierce et al., 2015; PMID: 26366722).

Product Class:	Purified
Clone ID:	2-3B2
Synonyms:	Slc6a2; Norepinephrine transporter; NET; Solute carrier family 6 member 2
Amount:	200 μg
Application Codes Clone:	WB; IHC; IP; ICC; IF
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody is specific for the sodium-dependent noradrenaline transporter. This antibody is an amine transporter. Terminates the action of noradrenaline by its high-affinity sodium-dependent reuptake into presynaptic terminals.
Application Notes:	Striatum tissues from 2- and 8-month-old wild-type and transgenic mice were immunoblotted using this antibody (Graham and Sidhu, 2010; PMID: 20077428). Freshly dissected mouse brain tissues were immunoblotted using this antibody (Ye et al., 2015; PMID: 26793096). This antibody was used for immunoblotting on protein from the mesenteric PVAT, mesenteric resistance vessels, adipocytes, SVF, and vena cava. The test animal used was a rat (Ayala-Lopez et al., 2015; PMID: 26432838). Mouse NET protein was immunoprecipitated using this antibody (Mannangatti et al., 2015; PMID: 25724654). Mouse NET protein was immunoblotted using this antibody (Mannangatti et al., 2015; PMID: 25724654). An immunoblot was performed on proteins from NET knockout mice using this antibody (Fentress et al., 2013; PMID: 24102798). Alvarial osteoblasts isolated from 3–4-day-old neonatal mice were immunoblotted using this antibody (Ma et al., 2013; PMID: 24005671). Immunocytochemistry was performed in formalin-fixed long bones of neonatal mice using this antibody (Ma et al., 2013; PMID: 24005671). Brain tissue from mice homozygous for a mutant human A53T-α-Syn transgene driven by the prion promoter (A53T) was immunoblotted with this antibody (Oaks et al., 2013; PMID: 23560093). Proteins from knock-in mice carrying the NET A457P allele were immunoblotted with this antibody (Shirley-Rice et al., 2013; PMID: 23580201). In a study investigating the role of the sodium-dependent vitamin C transporter-2 (SVCT2) in transporting VC at the cortical nerve terminal, this antibody was used for immunostaining on cultured SCG neurons (Pierce et al., 2015; PMID: 26366722).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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