Mfg Part Number
Ab02556-3.0
Vector Labs Ab02556-3.0 Anti-Inosine5'-monophosphate Dehydrogenase (IMPDH) [1D6-E3], Mouse IgG2b, kappa (200 μg)
Quick Overview
The antibody was generated by immunizing a mouse with the purified Chinese hamster IMPDH protein.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 1D6-E3 |
| Synonyms: | Inosine-5'-monophosphate dehydrogenase 2; IMPDH2; IMP dehydrogenase 2; IMPD 2; IMPDH 2; IMPDH-II |
| Amount: | 200 μg |
| Application Codes Clone: | WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2b |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody is specific for the IMPDH protein in both humans and rodents. IMPDH catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. |
| Application Notes: | This antibody was used for a western blot on proteins from E.coli cells that were made to express IMPDH (Hager et al, 1995; pmid:7763314). HL-205 cells were used in a peroxidase-based western blot with this antibody (Glesne et al, 1991; pmid:1717828). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |