Mfg Part Number
Ab02587-23.0

Vector Labs Ab02587-23.0 Anti-CIP2A [HL1925], Rabbit IgG, kappa (100 μg)

Quick Overview
The original antibody was generated by immunizing mice with C-terminal CIP2A as an immunogen.
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Product Class:Purified
Clone ID:HL1925
Synonyms:Cancerous inhibitor of protein phosphatase 2A; Cancerous inhibitor of PP2A; Protein CIP2A; p90 autoantigen; KIAA1524
Amount:100 μg
Application Codes Clone:IHC (P); WB
Shipping Temperature:Wet Ice
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG1
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:This antibody binds human CIP2A (cancerous inhibitor of protein phosphatase 2A). CIP2A is an oncoprotein that inhibits protein phosphatase 2A (PP2A), stabilizes MYC, and is involved in the progression of several human malignancies. It promotes anchorage-independent cell growth and tumor formation. Antibodies against CIP2A are present in sera from many patients with gastric or prostate cancer and acts as prognostic marker in many cancers.
Application Notes:This antibody can be used for the immunohistochemical staining of CIP2a expressed on the surface of prostate cancer, benign prostatic hyperplasia and high grade prostatic intraepithelial neoplasia tissues (PMID: 32860375). This antibody can be for the identification of CIP2a protein from cell lysates using western blot (PMID: 31031016).
More Information
Brand Vector Labs
UNSPSC 12161500