Mfg Part Number
Ab02601-23.0
Vector Labs Ab02601-23.0 Anti-IL-18 [E1], Rabbit IgG, kappa (200 μg)
Quick Overview
The original antibody was raised by immunizing BALB/c mice with recombinant chicken IL-18.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | E1 |
| Synonyms: | IGIF; Interleukin 18; interferon-y inducing factor; chIL18; Interleukin-18; IL 18; Chicken IL-18 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; WB; neutralizing |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody binds specifically to chicken IL-18, a cytokine that is produced by macrophages and other cells, and shows synergistic action with IL-12 to induce strong cell-mediated immunity following infection with microbial products, such as lipopolysaccharide. |
| Application Notes: | The specificity of the original antibody was confirmed by ELISA analysis. The antibody detected the recombinant chIL-18 by western blot analysis. The antibody neutralizes the biological function of chIL18 in HD11 cell and reduced IL-18-induced IFN-production by primary splenocytes. (Hong et al, 2010; pmid: 20674988). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |