Mfg Part Number
Ab02618-1.1

Vector Labs Ab02618-1.1 Anti-SARS-CoV-2 Spike protein (RBD monomer) [2B-G10-A1], Mouse IgG1, kappa (200 μg)

Quick Overview
The original mouse IgG1 version of this antibody was raised by immunizing BALB/c mice with a recombinant soluble trimeric SARS-CoV-2 Spike glycoprotein.
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Product Class:Purified
Clone ID:2B-G10-A1
Synonyms:Receptor Binding Domain; SARS CoV 2 S glycoprotein; COVID-19 Spike protein; RBD; Receptor Binding Domain; E2 glycoprotein; E2; Human coronavirus 2 spike glycoprotein; Peplomer protein; S glycoprotein; SARS coronavirus 2 S protein; SARS coronavirus 2 Spike Protein; SARS CoV 2 Spike protein; SARS CoV 2; SARS-CoV-2 S protein; SARSCoV2; SARS-COV-2 S protein; SARS-COV-2 Spike glycoprotein; SARSCOV2 Spike protein; Severe acute respiratory syndrome 2 spike glycoprotein; Severe acute respiratory syndrome virus 2 spike glycoprotein; Spike glycoprotein; 2019-nCoV; SARS-CoV2
Amount:200 μg
Application Codes Clone:ELISA
Shipping Temperature:Wet Ice
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG1
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Specificity Statement:This clone recognizes monomeric receptor binding domain (RBD) of the SARS-CoV-2 Spike protein as well as the full-length Spike protein. The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. The S protein is essential for both host specificity and viral infectivity. It's been reported that SARS-CoV-2 (COVID-19 coronavirus, 2019-nCoV) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Application Notes:This antibody is recommended for the detection and analysis of SARS-CoV-2 Spike protein receptor binding domain (RBD), especially in ELISA applications. Its binding to SARS-CoV-2 RBD was confirmed via ELISA.
More Information
Brand Vector Labs
UNSPSC 12161500