Mfg Part Number
Ab02618-10.7
Vector Labs Ab02618-10.7 Anti-SARS-CoV-2 Spike protein (RBD monomer) [2B-G10-A1], Human F(ab)2, AbFab2™ His-Tagged, kappa (100 μg)
Quick Overview
The original mouse IgG1 version of this antibody was raised by immunizing BALB/c mice with a recombinant soluble trimeric SARS-CoV-2 Spike glycoprotein.
$692.90
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| Product Class: | Purified |
|---|---|
| Clone ID: | 2B-G10-A1 |
| Heavy Chain Modification: | AbFab2™ His-Tagged |
| Synonyms: | Receptor Binding Domain; SARS CoV 2 S glycoprotein; COVID-19 Spike protein; RBD; Receptor Binding Domain; E2 glycoprotein; E2; Human coronavirus 2 spike glycoprotein; Peplomer protein; S glycoprotein; SARS coronavirus 2 S protein; SARS coronavirus 2 Spike Protein; SARS CoV 2 Spike protein; SARS CoV 2; SARS-CoV-2 S protein; SARSCoV2; SARS-COV-2 S protein; SARS-COV-2 Spike glycoprotein; SARSCOV2 Spike protein; Severe acute respiratory syndrome 2 spike glycoprotein; Severe acute respiratory syndrome virus 2 spike glycoprotein; Spike glycoprotein; 2019-nCoV; SARS-CoV2 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This clone recognizes monomeric receptor binding domain (RBD) of the SARS-CoV-2 Spike protein as well as the full-length Spike protein. The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. The S protein is essential for both host specificity and viral infectivity. It's been reported that SARS-CoV-2 (COVID-19 coronavirus, 2019-nCoV) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
| Application Notes: | This antibody is recommended for the detection and analysis of SARS-CoV-2 Spike protein receptor binding domain (RBD), especially in ELISA applications. Its binding to SARS-CoV-2 RBD was confirmed via ELISA. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |