Mfg Part Number
Ab02640-10.3
Vector Labs Ab02640-10.3 Anti-CD127 [1A11], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing Balb/c mice with the full ECD of CD127.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 1A11 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | IL7R; IL7Rα; IL-7Rα; Interleukin-7 receptor subunit alpha; IL-7 receptor subunit alpha; IL-7R-alpha; IL-7RA; CDw127 |
| Amount: | 200 μg |
| Application Codes Clone: | antagonist; ELISA; IHC; SPR; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for CD127 epitope regions 2, 3, 4 and 5. |
| Application Notes: | ELISA was performed on CD127 using this antibody (WO2010017468). This antibody was tested for inhibition of IL-7 induced IFN-γ and IL-17 in a TH17 expansion assay (WO2010017468). Surface plasmon resonance was used to assess the ability of this antibody to bind Fc effector receptors (Fc Gamma I, IIa and IIIa) (US9150653). Surface plasmon resonance was performed with this antibody on CD127 to test the binding affinity (WO2010017468). Immunohistochemistry was performed on the spinal cord of a mouse using this antibody (WO2010017468). Western blot was performed on protein extract using this antibody (WO2010017468). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |