Mfg Part Number
Ab02652-10.3
Vector Labs Ab02652-10.3 Anti-PD-1 [PD1-28], Human IgG1, Fc Silent™, lambda (200 μg)
Quick Overview
The original antibody was generated by panning against an scFv phagemid library generated from non-immunized human donors.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | PD1-28 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | CD279; Programmed cell death protein 1; PDCD1; PD-1; hPD-1 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; functional assay; block |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This full-length, reformatted human antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for PD-1. |
| Application Notes: | An ELISA was performed on PD-1 fusion protein using this antibody (US7488802). This antibody was capable of blocking the PD-1/PD-L1 interaction. It was found that PD1-28 can mimic PD-1 ligands and deliver an inhibitory signal causing a decrease in T cell proliferation and IL-2 production (US7488802). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |