Mfg Part Number
Ab02657-10.3
Vector Labs Ab02657-10.3 Anti-DLL4 [61B], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing mice with soluble human Dll4-His protein.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 61B |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | Delta-like protein 4; Drosophila Delta homolog 4; Delta4 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; IHC; IF; blocking |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for the EGF-like 3 domain of Dll4. |
| Application Notes: | U87MG and HT29 cells were immune-stained with this antibody (Zhou et al, 2015; pmid:26288060). This antibody is used for immunohistochemistry on U87MG and HT29 (Zhou et al, 2015; pmid:26288060). The 64Cu-chelator DOTA conjugated version of this antibody was used for the positron-emission tomography (PET) imaging of human glioblastoma and colorectal cancer xenografts (Zhou et al, 2015; pmid:26288060). This antibody was used for immunohistochemistry on spheroids and monolayers cells (US7906116). ELISA was performed with this antibody on Dll4 truncation mutants (US7906116). This antibody is able to block the Dll4-Notch1 interaction (US7906116). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |