Mfg Part Number
Ab02670-23.0
Vector Labs Ab02670-23.0 Anti-B7-H4 [#36-1], Rabbit IgG, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing BALB/c mice with recombinant human B7-H4 as immunogen.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | #36-1 |
| Synonyms: | B7H4; B7 homolog 4; B7h.5; O8E; Immune costimulatory protein B7-H4; B7S1; Protein B7S1; B7x; T-cell costimulatory molecule B7x; VTCN1 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; FC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds human B7-H4, which inhibits T cell proliferation and causes secretion of IL-2. It is overexpressed in breast, ovarian, endometrial, renal cell (RCC) and non-small-cell lung cancers (NSCLC). |
| Application Notes: | The binding specificity of this antibody towards B7-H4 was determined using ELISA. This antibody was used to screen B7-H4 positive human breast adenocarcinoma cell lines SKBR-3 using flow cytometry (US20180118831; Epstein Alan, 2013- B7-H4 as a Target for Breast Cancer Immunotherapy) |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |