Mfg Part Number
Ab02675-23.0
Vector Labs Ab02675-23.0 Anti-GXM [2H1], Rabbit IgG, kappa (200 μg)
Quick Overview
The original mouse version of this antibody was raised by infecting balb/c mice with C. neoformans and then immunizing them with glucuronoxylomannan-tetanus toxoid conjugate (GXM-TT).
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 2H1 |
| Synonyms: | Glucuronoxylomannan; Cryptococcus neoformans capsular polysaccharide; CNPS |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; therapeutic |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for GXM from C.neoformans. GXM is a polysacharide experssed on the surface of c.neoformans. |
| Application Notes: | To characterize the mouse version of this antibody an ELISA was performed on native and de-O-acetylated serotype A GMX using the mouse version of this antibody (Casadevall et al, 1992; pmid:1583327). In research on the efficacy of the mouse version of this antibody against diverse strains of Cryptococcus neoformans. This antibody showed the ability to reduce the amount of yeast cells present in the organs of mice (Mukherjee et al, 1995; pmid:7642262). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |