Mfg Part Number
Ab02725-23.0
Vector Labs Ab02725-23.0 Anti-CD138 [587CT7.3.6.5.2], Rabbit IgG, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing female BALB/c mice with myeloma tumor cells or CD138 protein antigen.
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| Product Class: | Purified |
|---|---|
| Clone ID: | 587CT7.3.6.5.2 |
| Synonyms: | Syndecan-1; SDC1; SYND1; SDC |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; WB; IF; FC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgM |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgM format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for the extracellular domain of human syndecan-1. Syndecan-1 is a cell membrane protein that, after its shedding by heparanase enzymes, is accumulated in the extracellular matrix of some tumours, e.g. myeloma and lung carcinoma, where it modulates several key processes of tumourigenesis such as cancer cell proliferation and apoptosis, angiogenesis and metastasis. |
| Application Notes: | The screening of hybridomas for specific antibodies was done using ELISA. Further confirmation of the specificity for CD138 was done using western blotting. This antibody was also used for immunofluorescent staining and Flow cytometric analysis of CD138 exoression on HepG2, T47D and U266 cells (CN104059151). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |