Vector Labs Ab02742-10.7 Anti-Spike protein [D70678-5521-S2], Human F(ab)2, AbFab2™ His-Tagged, kappa (100 μg) Centrifuge Bundle Savings at Sycamore Life Sciences

Description

Product Class: Purified
Clone ID: D70678-5521-S2
Heavy Chain Modification: AbFab2™ His-Tagged
Synonyms: SARS CoV 2 S glycoprotein; COVID-19 Spike protein; RBD; Receptor Binding Domain; E2 glycoprotein; E2; Human coronavirus 2 spike glycoprotein; Peplomer protein; S glycoprotein; SARS coronavirus 2 S protein; SARS coronavirus 2 Spike Protein; SARS CoV 2 Spike protein; SARS CoV 2; SARS-CoV-2 S protein; SARSCoV2; SARS-COV-2 S protein; SARS-COV-2 Spike glycoprotein; SARSCOV2 Spike protein; Severe acute respiratory syndrome 2 spike glycoprotein; Severe acute respiratory syndrome virus 2 spike glycoprotein; Spike glycoprotein; 2019-nCoV
Amount: 100 μg
Application Codes Clone: ELISA; SPR; functional assay
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This reformatted human antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody is specific for the spike protein of SARS CoV2. SARS‑CoV‑2 is a positive-sense single-stranded RNA virus[5] that is contagious in humans.
Application Notes: To characterize this antibody, an indirect ELISA was performed using the human version of this antibody. The antigen used was the SARS CoV2 spike protein. The human version of this antibody is capable of binding the S1 protein but incapable of blocking S1:ACE2 interaction. This antibody is reported to bind non-competitively with another anti-SARS CoV2 antibody 18F4. Further both biolayer interferometry and surface plasmon resonance were used to determine the kinetics of the human version of this antibody. Both experiments used the SARS CoV2 spike protein as the antigen (Mullen et al, 2021).

Product Class:	Purified
Clone ID:	D70678-5521-S2
Heavy Chain Modification:	AbFab2™ His-Tagged
Synonyms:	SARS CoV 2 S glycoprotein; COVID-19 Spike protein; RBD; Receptor Binding Domain; E2 glycoprotein; E2; Human coronavirus 2 spike glycoprotein; Peplomer protein; S glycoprotein; SARS coronavirus 2 S protein; SARS coronavirus 2 Spike Protein; SARS CoV 2 Spike protein; SARS CoV 2; SARS-CoV-2 S protein; SARSCoV2; SARS-COV-2 S protein; SARS-COV-2 Spike glycoprotein; SARSCOV2 Spike protein; Severe acute respiratory syndrome 2 spike glycoprotein; Severe acute respiratory syndrome virus 2 spike glycoprotein; Spike glycoprotein; 2019-nCoV
Amount:	100 μg
Application Codes Clone:	ELISA; SPR; functional assay
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This reformatted human antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody is specific for the spike protein of SARS CoV2. SARS‑CoV‑2 is a positive-sense single-stranded RNA virus[5] that is contagious in humans.
Application Notes:	To characterize this antibody, an indirect ELISA was performed using the human version of this antibody. The antigen used was the SARS CoV2 spike protein. The human version of this antibody is capable of binding the S1 protein but incapable of blocking S1:ACE2 interaction. This antibody is reported to bind non-competitively with another anti-SARS CoV2 antibody 18F4. Further both biolayer interferometry and surface plasmon resonance were used to determine the kinetics of the human version of this antibody. Both experiments used the SARS CoV2 spike protein as the antigen (Mullen et al, 2021).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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