Mfg Part Number
Ab02762-10.3
Vector Labs Ab02762-10.3 Anti-Estradiol-17β [E4-4], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
This antibody was raised by immunizing a female balb/c mouse with immunogenic Estradiol-17β-BSA conjugate.
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| Product Class: | Purified |
|---|---|
| Clone ID: | E4-4 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | 17-beta-estradiol; E2; ethynyl estradiol; estradiol; oestradiol; ChEBI: 16469 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; RIA; SPR |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 18824188 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for Estradiol-17β. Estradiol-17β is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of the estrous and menstrual female reproductive cycles. |
| Application Notes: | The scFv version of this antibody is capable of binding E2-7-BSA in an ELISA. A radioimmunoassay was performed using E2 standard and E2 with [H3] using the mouse version and the scFv version of this antibody. Finally the association and dissociation rate were determined using surface plasmon resonance on E2-7-BSA using both the mouse version and the scFv version of this antibody (Kobayashi et al, 2008; pmid:18824188) (Kobayashi et al, 2010; pmid:20047279). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |