Mfg Part Number
Ab02837-1.1
Vector Labs Ab02837-1.1 Anti-Cytochrome C [E8], Mouse IgG1, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing BALB/c mice with horse cytochrome c (cyt c) conjugated to hemocyanin.
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| Product Class: | Purified |
|---|---|
| Clone ID: | E8 |
| Synonyms: | CYC; CYCS; FabE8; Fab E8 |
| Amount: | 200 μg |
| Application Codes Clone: | RIA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody binds horse cytochrome c. This antibody recognizes three major discontiguous segments (33 to 39; 56 to 66; 96 to 104), and two minor sites on cyt c opposite to the exposed haem edge (PMID: 9698550). |
| Application Notes: | The original mouse IgG1 version of this antibody binds horse cytochrome c with an affinity of Kd ≃ 10(−9) M (PMID: 2993413). A solid phase radioimmunoassay was used to identify the specific epitope that the antibody binds (PMID: 2454225). The structural mechanism involved in the binding of the IgG1 antibody E8 to its highly charged protein antigen horse cytochrome c (cyt c) was studied using crystallographic structures (PMID: 9698550). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |