Vector Labs Ab02840-10.0 Anti-Melan-A [A103], Human IgG1, kappa (200 μg) Centrifuge Bundle Savings at Sycamore Life Sciences

Description

Product Class: Purified
Clone ID: A103
Synonyms: MART-1; MART1; Melan A; MLANA; Antigen LB39-AA; Antigen SK29-AA; Protein Melan-A; Melanoma antigen recognized by T-cells 1; MALENA
Amount: 200 μg
Application Codes Clone: ELISA; WB; IP; IHC;
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Specificity Statement: This antibody binds human Melan-A protein. This protein is found on the surface of melanocytes and is an important marker for detection of melanocytic tumors.
Application Notes: The binding characterization of this antibody towards Melan-A was done using ELISA. The original mouse IgG1 antibody was able to detect Melan-A from cell lysates of SK-MEL-13, SK-MEL-23, and SK-MEL-28 cell lines in an immunoblot assay. This antibody was also able to immunoprecipitate Melan-A protein from cell lysates of SK-MEL-13, SK-MEL-23, and SK-MEL-28 cell lines. The original mouse antibody was also used in the immunohistochemical analysis of normal skin and two Melan-A positive melanomas SK-MEL-19 and MZ2-MEL3.1 (PMID: 8650193). This antibody was used for detection of Melan-A antigen on formalin-fixed, paraffin-embedded tissues and in diagnosis of metastatic melanoma (PMID: 9591730). Immunohistochemical analysis with this antibody was useful in the differential diagnosis of adrenocortical neoplasms from both renal cell and hepatocellular carcinomas (PMID: 14663359; 9422316). This antibody has also been explored in the differential diagnosis of ovarian sex cord stromal tumours using immunohistochemistry (PMID: 10823140).

Product Class:	Purified
Clone ID:	A103
Synonyms:	MART-1; MART1; Melan A; MLANA; Antigen LB39-AA; Antigen SK29-AA; Protein Melan-A; Melanoma antigen recognized by T-cells 1; MALENA
Amount:	200 μg
Application Codes Clone:	ELISA; WB; IP; IHC;
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Specificity Statement:	This antibody binds human Melan-A protein. This protein is found on the surface of melanocytes and is an important marker for detection of melanocytic tumors.
Application Notes:	The binding characterization of this antibody towards Melan-A was done using ELISA. The original mouse IgG1 antibody was able to detect Melan-A from cell lysates of SK-MEL-13, SK-MEL-23, and SK-MEL-28 cell lines in an immunoblot assay. This antibody was also able to immunoprecipitate Melan-A protein from cell lysates of SK-MEL-13, SK-MEL-23, and SK-MEL-28 cell lines. The original mouse antibody was also used in the immunohistochemical analysis of normal skin and two Melan-A positive melanomas SK-MEL-19 and MZ2-MEL3.1 (PMID: 8650193). This antibody was used for detection of Melan-A antigen on formalin-fixed, paraffin-embedded tissues and in diagnosis of metastatic melanoma (PMID: 9591730). Immunohistochemical analysis with this antibody was useful in the differential diagnosis of adrenocortical neoplasms from both renal cell and hepatocellular carcinomas (PMID: 14663359; 9422316). This antibody has also been explored in the differential diagnosis of ovarian sex cord stromal tumours using immunohistochemistry (PMID: 10823140).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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