Mfg Part Number
Ab02857-23.0
Vector Labs Ab02857-23.0 Anti-Nipah virus F1 [13G5], Rabbit IgG, kappa (200 μg)
Quick Overview
The original version of this antibody was raised against the fusion (F) protein of the Nipah virus.
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| Product Class: | Purified |
|---|---|
| Clone ID: | 13G5 |
| Synonyms: | NiV; Fusion glycoprotein; Protein F; Fusion glycoprotein F1; Nipah henipavirus |
| Amount: | 200 μg |
| Application Codes Clone: | WB; IP |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific to the F1 chain of the fusion (F) protein of the Nipah virus. It is a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. This clone binds to the post fusion form. It crossreacts with HeV F. |
| Application Notes: | This antibody is recommened for the detection and analysis of the fusion (F) protein of the Nipah virus. This clone is specifically useful in Western blot identification of F1 version of the protein. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |