Mfg Part Number
Ab02878-10.3
Vector Labs Ab02878-10.3 Anti-CD49F [GoH3], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
This antibody was raised by immunizing a BALB/c rat with amino acids 1242-1255 of the C-terminus of the Human c-erbB-2/HER-2/neu protein
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| Product Class: | Purified |
|---|---|
| Clone ID: | GoH3 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | Integrin alpha-6; ITGA6; CD49 antigen-like family member F; VLA-6 |
| Amount: | 200 μg |
| Application Codes Clone: | IHC; FC; IF |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Rat IgG2a format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody is specific for the mouse, human and dog version of the CD49F protein. CD49F is a receptor for laminin on platelets. Furthermore CD49F is present in oocytes and is involved in sperm-egg fusion. |
| Application Notes: | To determine the influence of anti-CD49f and anti-CD29 monoclonal antibodies on mitotic activity of epithelial cells, cryo-sections of human cultured gingiva were stained for immunohistochemistry using the mouse version of this antibody. (Becker et al, 2002; pmid:12013557). To isolate pancreatic islet progenitor cells from foetal mice, a mouse pancreatic cell dispersion was used for flow cytometry using the mouse version of this antibody (Sugiyama et al, 2006; pmid:17190805). To present evidence that HPV binds specifically to laminin 5, cultured keratinocytes infected with VLPs from HPV-11, were stained using the mouse version of this antibody (Culp et al, 2006; pmid:16940506). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |